Staphylococcus Aureus iyo Methicillin-iska-caabbinta Staphylococcus Aureus Nucleic Acid

Staphylococcus aureus waa mid ka mid ah bakteeriyada pathogenic ee ugu muhiimsan ee caabuqa nosocomial.Staphylococcus aureus (SA) waxay ka tirsan tahay staphylococcus waxayna wakiil ka tahay bakteeriyada Gram-positive, taas oo soo saari karta noocyo kala duwan oo sun ah iyo enzymes soo jiidasho leh.Bakteeriyadu waxay leedahay sifooyinka qaybinta ballaaran, cudur-sidaha xooggan iyo heerka caabbinta sare.Hidda-wadaha Thermostable nuclease (nuc) waa hidde-sidaha aadka loo ilaaliyo ee staphylococcus aureus.Sannadihii ugu dambeeyay, isticmaalka badan ee hormoonnada iyo diyaargarowga difaaca iyo ku-takri-falka antibiyootiga ballaaran, caabuqyada nosocomial ee ay keento Staphylococcus aureus ee Methicillin-adkeysiga (MRSA) ee Staphylococcus ayaa kor u kacay.Celceliska heerka ogaanshaha qaran ee MRSA wuxuu ahaa 30.2% sanadka 2019 gudaha Shiinaha.MRSA waxay u qaybsantaa MRSA-caafimaad-ku-xiran MRSA (HA-MRSA), bulshada-ku xidhan MRSA (CA-MRSA), iyo xoolaha-Xooluhu MRSA (LA-MRSA).CA-MRSA, HA-MRSA, LA-MRSA waxay leeyihiin kala duwanaansho weyn xagga microbiology, caabbinta bakteeriyada (tusaale, HA-MRSA waxay muujinaysaa caabbinta daawooyinka badan marka loo eego CA-MRSA) iyo sifooyin caafimaad (tusaale goobta caabuqa).Marka loo eego sifooyinkan, CA-MRSA iyo HA-MRSA waa la kala saari karaa.Si kastaba ha ahaatee, farqiga u dhexeeya CA-MRSA iyo HA-MRSA waa sii yaraanaya sababtoo ah dhaqdhaqaaqa joogtada ah ee dadka ee ka dhexeeya isbitaalada iyo bulshada.MRSA waa iska caabbinta dawooyinka badan, ma aha oo kaliya adkaysi u leh antibiyootiga β-lactam, laakiin sidoo kale aminoglycosides, macrolides, tetracyclines iyo quinolones ilaa heerar kala duwan.Waxaa jira kala duwanaansho weyn oo heer gobol ah oo ku saabsan heerarka iska caabbinta daroogada iyo isbeddellada kala duwan.

Hiddaha-sidaha mecA-ga iska caabbinta Meticillin ayaa door muhiim ah ka ciyaara iska caabbinta staphylococcal.Hidde-sidaha waxaa lagu qaadaa unug gaar ah oo hidde-side mobilada ah (SCCmec), kaasoo qeexaya borotiinka penicillin-ku-xidha 2a (PBP2a) wuxuuna xiriir hoose la leeyahay antibiyootigyada β-lactam, si ay dawooyinka lidka-ku-ciyaarku u hor istaagi karaan isku-dhafka lakabka unugga ee peptidoglycan. taasoo keentay iska caabin daroogo.