Human Leukocyte Antigen B27 Nucleic Acid
Magaca alaabta
HWTS-GE011A-Human Leukocyte Antigen B27 Qalabka Lagu Ogaado Asiidhka Nucleic (Fluorescence PCR)
Epidemiology
Ankylosing spondylitis (AS) waa cudur barar barar ah oo daba-dheeraaday kaasoo inta badan ku dhaca laf dhabarta waxaana laga yaabaa inuu ku lug yeesho kala-goysyada sacroiliac iyo kala-goysyada ku xeeran ilaa heerar kala duwan.Waxa la daaha ka qaaday in AS ay muujiso isu-urur qoys oo muuqda oo ay si dhow ula xidhiidhaan antigen-ka leukocyte HLA-B27.Bini'aadamka, in ka badan 70 nooc oo HLA-B27 ah ayaa la helay oo la aqoonsaday, waxaana ka mid ah, HLA-B*2702, HLA-B*2704 iyo HLA-B*2705 waa noocyada ugu badan ee la xidhiidha cudurka.Shiinaha, Singapore, Japan iyo degmada Taiwan ee Shiinaha, nooca-hoosaadka ugu caansan ee HLA-B27 waa HLA-B*2704, oo xisaabiya qiyaastii 54%, oo ay ku xigto HLA-B*2705, taas oo xisaabisa qiyaastii 41%.Qalabkani wuxuu ku ogaan karaa DNA-da nooc-hoosaadyada HLA-B*2702, HLA-B*2704 iyo HLA-B*2705, laakiin midba midka kale kama sooco.
Kanaalka
| FAM | HLA-B27 |
| VIC/HEX | Xakamaynta Gudaha |
Qiyaasaha Farsamada
| Kaydinta | Dareeraha: ≤-18℃ Madow |
| Nolosha shelf | Dareeraha: 18 bilood |
| Nooca Tuunada | shaybaar dhiig oo dhan |
| Ct | ≤40 |
| CV | ≤5.0% |
| LoD | 1ng/μL |
| Gaar ahaan
| Natiijooyinka baaritaanka ee xirmadani ma saameyn doonto hemoglobin (<800g/L), bilirubin (<700μmol/L), iyo dufannada dhiigga/ triglycerides (<7mmol/L) ee dhiigga. |
| Qalabka lagu dabaqi karo | Nidaamyada noolaha ee la dabaqay 7500 Nidaamyada PCR-waqtiga-dhabta ah Hababka noolaha ee la dabaqay StepOne Nidaamyada PCR-waqtiga-dhabta ah LightCycler®480 Nidaamka PCR-waqtiga-dhabta ah Agilent-Stratagene Mx3000P Nidaamka Q-PCR |
